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. 2013 Mar 13;33(11):4875–4885. doi: 10.1523/JNEUROSCI.4111-12.2013

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Copyright © 2013 the authors 0270-6474/13/334875-11$15.00/0

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Figure 7. — 5-HT reduces the intensity and variation of monosynaptic STN→SNr EPSCs in SNr GABA neurons. The stimulating electrode was placed in the SNr. A train of 10 stimulating pulses with interpulse interval of 50 ms were used. A, Averaged EPSCs evoked by the train of 10 pulse stimulation before and during 10 μm 5-HT application. B, Pooled data showing the inhibitory effect of 10 μm 5-HT on the peak amplitude of a train of 10 EPSCs in eight SNr GABA neurons. C, Pooled data showing the increased ratios of EPSC_n/EPSC₁ in the eight SNr GABA neurons during 10 μm 5-HT application. Recovery data were not shown for clarity of the graph. $, p < 0.05 for the ratios of EPSC₂/EPSC₁ through EPSC₁₀/EPSC₁ under control versus during 10 μm 5-HT. Repeated-measures ANOVA was used.