Skip to main content
. Author manuscript; available in PMC: 2013 Apr 5.
Published in final edited form as: J Med Chem. 2005 Aug 25;48(17):5551–5560. doi: 10.1021/jm0501228

Scheme 1a.

Scheme 1a

a Reagents and conditions: (a) K2CO3, MeOH; (b) NaBH4, EtOH, rt; (c) 85% H3PO4, 60 °C; (d) H2, 10% Pd/C, MeOH, 45 psi; (e) Zn/Hg, HCl (5%), reflux; (f) CrO3, H2SO4, acetone, 0 °C; (g) H2, 10% Pd/C, 10% HOAc/MeOH, 45 psi.