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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Radiat Res. 2012 Dec 13;179(2):125–134. doi: 10.1667/RR2954.1

FIG. 2.

FIG. 2

Breathing rate (mean breaths per minute) as a function of time after irradiation. Panels A and B: CON = no irradiation (soy-free diet); LR = whole lung irradiation (12 Gy); LR + PEG = whole lung irradiation (12 Gy) plus daily injections of polyethylene glycol (PEG); Gen = daily subcutaneous (sc) injections of 50 mg/kg genistein (dissolved in PEG); EUK = daily sc injections of EUK-207. The drug treatments were started 0 or 2 weeks post irradiation and terminated at 28 weeks. In two groups of rats, the drugs were crossed over at 14 weeks post irradiation (Gen/EUK or EUK/Gen). The rats were euthanized at 48 weeks. Also shown in panel A is data from our previous experiment (18) for adult rats given 12 Gy whole-lung irradiation, as indicated. Each point represents the mean (±SEM) for all rats available for analysis at different times.