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. 2013 Mar;54(3):622–635. doi: 10.1194/jlr.M030650

TABLE 2.

Regression analysis of correlation between immunosuppression capacity and the best lipid indicators in hBMSCs

Lipid or Fatty Acid Indicator Correlation Coefficient R2 P Value Range (mol%)
PC38:4(chains 18:0, 20:4n-6) −0.91 0.84 0.001 4.7–7.7
PC38:5(chains 18:1, 20:4n-6) −0.82 0.68 0.012 4.2–6.3
PC34:1(chains 16:0, 18:1) +0.80 0.64 0.017 23.5–27.0
PC38:4/PC34:1 −0.90 0.81 0.003 0.17–0.33
20:4n-6 −0.71 0.50 0.050 6.1–9.6
22:6n-3 +0.75 0.56 0.032 2.0–3.3
20:4n-6/22:6n-3 −0.76 0.58 0.029 2.2–4.9

The hBMSCs (n = 8, all cultured until passage 4) suppressed T- cell proliferation in a coculture assay (degree of inhibition with hBMSC:PBMC ratio 1:20; range, 70–88%) and relative amounts of selected lipid and fatty acid indicators or their ratios in the cells.