TABLE 3.
Differentially expressed genes
| Mean Fold Change | ||||
| Description | HGNC | Gene ID | o4-y4 | o8-o4 |
| Lipid metabolism | ||||
| 1-acylglycerol-3-phosphate O-acyltransferase 2 | AGPAT2 | 10555 | 0.6 | |
| ATPase, class V, type 10A (aminophospholipid translocase) | ATP10A | 57194 | 0.7 | |
| Choline kinase β | CHKB | 1120 | −1.2 | |
| CD36 molecule (thrombospondin receptor)] | CD36 | 948 | 4.4 | |
| ELOVL fatty acid elongase 3 | ELOVL3 | 83401 | −1.0 | |
| Ethanolamine kinase 2 | ETNK2 | 55224 | −0.8 | |
| Fatty acid desaturase 1(delta -5–desaturase) | FADS1 | 3992 | −1.4 | |
| Fatty acid desaturase 2(delta-6-desaturase) | FADS2 | 9415 | −1.6 | |
| Fat storage-inducing transmembrane protein 2 | FITM2 | 128486 | 0.7 | |
| Inositol 1,4,5-trisphosphate receptor, type 1 | ITPR1 | 3708 | 1.0 | |
| Leukotriene C4 synthase | LTC4S | 4056 | −1.3 | |
| Lysophosphatidylcholine acyltransferase 2 | LPCAT2 | 54947 | −2.2 | |
| Lysophosphatidylcholine acyltransferase 3 | LPCAT3 | 10162 | −0.7 | |
| Phospholipid scramblase 1 | PLSCR1 | 5359 | −0.9 | |
| Phospholipid scramblase 4 | PLSCR4 | 57088 | 1.1 | |
| Prostaglandin-endoperoxide synthase 1 | PTGS1 | 5742 | −0.7 | |
| Prostaglandin I2 (prostacyclin) receptor (IP) | PTGIR | 5739 | 0.7 | |
| Scavenger receptor class B, member 1 | SCARB1 | 949 | −1.9 | |
| Serine palmitoyltransferase, long chain base subunit 3 | SPTLC3 | 55304 | −0.6 | |
| Stearoyl-CoA desaturase (delta-9-desaturase) | SCD | 6319 | −2.4 | 1.1 |
| Immune response | ||||
| Alpha-2-macroglobulin | 2 | −3.8 | ||
| Ankyrin repeat and SOCS box containing 2 | ASB2 | 51676 | −1.2 | |
| Ankyrin repeat and SOCS box containing 5 | ASB5 | 140458 | 1.0 | |
| Ankyrin repeat and SOCS box containing 10 | ASB10 | 136371 | −0.9 | |
| Bradykinin receptor B1 | BDKRB1 | 623 | −3.9 | |
| CD74 molecule, major histocompatibility complex, class II invariant chain | CD74 | 972 | −0.7 | |
| Complement component 3a receptor 1 | C3AR1 | 719 | 1.0 | |
| Interferon (α, β and omega) | IFNAR2 | 3455 | −0.9 | |
| Interleukin 6 | IL6 | 3569 | 0.7 | |
| Interleukin 26 | IL26 | 55801 | −1.4 | |
| Linker for activation of T cells family member 2 | LAT2 | 7462 | −0.9 | |
| Major histocompatibility complex, class II, DM α | HLA-DMA | 3108 | −2.0 | |
| Major histocompatibility complex, class II, DM β | HLA-DMB | 3109 | −2.0 | |
| Major histocompatibility complex, class II, DR α | HLA-DRA | 3122 | −2.1 | |
| Suppressor of cytokine signaling 1 | SOCS1 | 8651 | −0.6 | |
| Suppressor of cytokine signaling 3 | SOCS3 | 9021 | −1.0 | −0.8 |
| Transforming growth factor, β receptor 1 | TGFBR1 | 7046 | 1.2 | |
Differentially expressed genes related to lipid metabolism and immune response. o4-y4, comparison between old and young donor samples in passage 4; o8-o4, comparison between old donor samples in passages 8 and 4.