Table 1.
Functional gene ontology annotation using DAVID
|
Up-regulated |
|
Down-regulated |
|
||
|---|---|---|---|---|---|
| Pathway | % | P value | Pathway | % | P value |
| gga04142:Lysosome |
3.32 |
0.0155 |
gga04520:Adherens junction |
2.97 |
0.0000 |
| gga00190:Oxidative phosphorylation |
3.32 |
0.0420 |
gga04060:Cytokine-cytokine receptor interaction |
2.97 |
0.0456 |
| gga04620:Toll-like receptor signaling pathway |
2.90 |
0.0213 |
gga03010:Ribosome |
2.75 |
0.0004 |
| gga04621:NOD-like receptor signaling pathway |
2.07 |
0.0259 |
gga04514:Cell adhesion molecules (CAMs) |
2.54 |
0.0153 |
| |
|
|
gga04142:Lysosome |
2.33 |
0.0300 |
| gga04350:TGF-beta signaling pathway | 1.91 | 0.0483 | |||
The gene list containing the 559 up-regulated and 1198 down-regulated differentially expressed genes in duck spleen common to all three LPAIV infections at 3 dpi was entered into the DAVID functional annotation software. The following KEGG pathways are enriched in the dataset. The percentage column indicates percentage of differentially expressed genes that mapped to the DAVID database with a corresponding significance value (p<0.05).