Table 6. Descriptive statistics of all study participant serum samples tested for “10-plex” Panel (TNF-α, IL-1β, IL-6, IFN-γ, IL-4, IL-10, IL-2, IL-5, IL-8, GM-CSF) and “4-plex” Panel (TNF-α and MCP-1).
Analyte | GM-CSF | IFN-γ | IL-10 | IL-1β | IL-2 | IL-4 | IL-5 | IL-6 | IL-8 | TNF-α1 | MCP-1 | TNF-α2 |
(Unit) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) |
Total N Tested | 1320 | 1320 | 1320 | 1320 | 1320 | 1320 | 1320 | 1320 | 1320 | 1320 | 1320 | 1320 |
Total N Pass QC | 1226 | 1226 | 1320 | 1109 | 1226 | 1226 | 1226 | 1226 | 1320 | 1226 | 1226 | 1138 |
% below | 60.44 | 33.77 | 17.05 | 33.27 | 4.32 | 64.68 | 4.08 | 0 | 0 | 0 | 3.16 | |
% above | 0.73 | 0 | 0 | 0 | 0 | 0.08 | 0 | 0.24 | 0 | 0.16 | 0 | 0 |
N | 476 | 812 | 1095 | 740 | 1173 | 1225 | 433 | 1173 | 1320 | 1224 | 1226 | 1102 |
Mean(SD) | 33.34(80.01) | 0.746(3.34) | 10.89(45.84) | 1.32(2.35) | 2.79(11.94) | 5.73(21.39) | 2.70(10.64) | 4.33(20.31) | 13.12(17.57) | 4.16(14.83) | 143.3(66.49) | 1.72(0.758) |
Min | 1.46 | 0.111 | 0.276 | 0.083 | 0.164 | 0.39 | 0.254 | 0.162 | 0.592 | 0.181 | 1.24 | 0.56 |
25th percentile | 3.46 | 0.223 | 0.598 | 0.37 | 0.44 | 1.26 | 0.454 | 0.515 | 6.51 | 0.935 | 99.34 | 1.27 |
Median | 7.23 | 0.316 | 1.01 | 0.622 | 0.681 | 1.68 | 0.657 | 0.877 | 9.28 | 1.43 | 134.5 | 1.59 |
75th percentile | 21.1 | 0.486 | 2.7 | 1.25 | 1.39 | 2.82 | 1.28 | 1.89 | 13.82 | 2.64 | 179.1 | 1.98 |
Max | 888 | 86.5 | 633.5 | 28.45 | 241.4 | 360.2 | 129.5 | 379 | 322.6 | 350.3 | 471.6 | 13.14 |
Total N Tested; number of participant samples sent for testing, Total N pass QC; number of participant samples after removal of failed QC batches,
% above/below; percent of samples to pass QC but fall above or below the quantifiable range of the assay based on table 3.
1– TNF-α assayed as part of the 10-Plex.
2– TNF-α assayed with MCP-1.