Table 7. Descriptive statistics of all study participant saliva samples tested for Bone Panel (osteoprotegrin (OPG), leptin, parathyroid hormone (PTH) and insulin), Matrix Metalloproteinase Panel (MMP-2, MMP-8, MMP-9) and Obesity Panel (adiponectin and C-reactive protein (CRP)).

Analyte	Insulin	Leptin	OPG	PTH	MMP-2	MMP-8	MMP-9	Adiponectin	CRP
(Unit)	(ng/mL)	(ng/mL)	(pg/mL)	(pg/mL)	(pg/mL)	(pg/mL)	(pg/mL)	(ng/mL)	(ng/mL)
Total N Tested	1133	1133	1133	1133	1133	1133	1133	1133	1133
Total N Pass QC	1133	1133	1133	1059	820	1133	1133	1062	968
% below	5.83	9.89	0.35	2.83	83.29	0.44	0.09	0.47	2.58
% above	0	0	0	0	0	6.47	31.71	1.6	0.1
N	1067	1021	1129	1029	136	1050	768	1040	942
Mean(SD)	0.484(0.579)	0.362(0.205)	167.6169.9)	21.425.7)	5,6975,840)	214,728179,177)	224,126122,263)	22.8132.3)	0.9921.66)
Min	0.037	0.06	2.84	0.449	2,134	1,259	254.9	0.068	0.002
25th percentile	0.146	0.208	72.43	4.87	2,840	79,866	125,687	6.13	0.154
Median	0.278	0.321	115.5	11.2	3,487	161,302	214,383	11.8	0.438
75th percentile	0.622	0.467	203.7	27.8	6,015	296,368	317,275	25.2	1.12
Max	5.31	1.57	2,293	185.6	33,807	1,049,129	532,426	276.7	25.9

Total N Tested; number of participant samples sent for testing, Total N pass QC; number of participant samples after removal of failed QC batches

% above/below; percent of samples to pass QC but fall above or below the quantifiable range of the assay based on table 3.