Table 8. Descriptive statistics of all study participant saliva samples tested for “10-plex” Panel (TNF-α, IL-1β, IL-6, IFN-γ, IL-4, IL-10, IL-2, IL-5, IL-8, GM-CSF) and “4-plex” Panel (TNF-α and MCP-1).
Analyte | GM-CSF | IFN-γ | IL-10 | IL-1β | IL-2 | IL-4 | IL-5 | IL-6 | IL-8 | TNF-a1 | MCP-1 | TNF-a2 |
(Unit) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) | (pg/mL) |
Total N Tested | 1133 | 1133 | 1133 | 1133 | 1133 | 1133 | 1133 | 1133 | 1133 | 1133 | 1133 | 1133 |
Total N Pass QC | 1133 | 1133 | 1133 | 1133* | 1133 | 1133 | 1133 | 1133 | 1133* | 1133 | 1039 | 1042 |
% below | 74.03 | 37.99 | 32.36 | 0.53 | 5.21 | 2.3 | 68.55 | 0.71 | 0 | 3.18 | 0.29 | 5.37 |
% above | 0.88 | 1.5 | 0.18 | 11.58 | 0.53 | 0.97 | 0.09 | 1.86 | 81.79 | 2.74 | 3.37 | 0 |
N | 284 | 685 | 763 | 994 | 1067 | 1094 | 355 | 1102 | 206 | 1065 | 1001 | 986 |
Mean(SD) | 39.77(100.2) | 21.48(134.3) | 11.8(55.0) | 61.3(69.5) | 9.64(44.8) | 26.0(111.3) | 17.1(60.9) | 14.2(40.7) | 413.2(188.5) | 20.6(36.8) | 374.1(360.3) | 5.27(7.17) |
Min | 1 | 0.073 | 0.178 | 0.48 | 0.119 | 0.35 | 0.178 | 0.106 | 0.74 | 0.132 | 1.77 | 0.526 |
25th percentile | 3.61 | 0.213 | 0.706 | 21.1 | 0.711 | 2.25 | 0.682 | 1.59 | 254 | 4.3 | 143.6 | 1.97 |
Median | 8.15 | 0.836 | 1.62 | 38.1 | 1.32 | 4.98 | 1.84 | 4.14 | 436.1 | 8.96 | 244.7 | 3.32 |
75th percentile | 27.04 | 4.61 | 3.93 | 73.0 | 3.45 | 11.63 | 5.05 | 10.46 | 578.2 | 19.01 | 471.3 | 5.83 |
Max | 799.5 | 2,425 | 669.1 | 421.6 | 872.1 | 1,854 | 480.4 | 621.6 | 705.4 | 411.1 | 2,303 | 86.88 |
Total N Tested; number of participant samples sent for testing, Total N pass QC; number of participant samples after removal of failed QC batches.
% above/below; percent of samples to pass QC but fall above or below the quantifiable range of the assay based on table 3.
1– TNF-α assayed as part of the 10-Plex.
2– TNF-α assayed with MCP-1.
- the QC material was insufficient for evaluation of these analytes, all data within analytic range is reported and has not been adjusted by batch.