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. 2013 Apr 5;8(4):e59981. doi: 10.1371/journal.pone.0059981

Table 3. Evaluation of toxicity.

Arm A Arm B
N (%) N (%)
Constipation No 17 (47.2) 12 (33.3)
Yes 19 (52.8) 24 (66.7)
p-value 0.34
Nausea No 26 (72.2) 20 (55.6)
Yes 10 (27.8) 16 (44.4)
p-value 0.22
Drowsiness No 20 (55.6) 16 (44.4)
Yes 16 (44.4) 20 (55.6)
p-value 0.48
Confusion No 30 (83.3) 26 (72.2)
Yes 6 (16.7) 10 (27.8)
p-value 0.40
Itching No 33 (91.7) 29 (80.6)
Yes 3 (8.3) 7 (19.4)
p-value 0.31
Other No 29 (80.6) 22 (61.1)
Yes 7 (19.4) 14 (38.9)
p-value 0.12