Figure 6. Oral vaccination using A.C.NPs-legumain inhibits tumor growth and increases survival in orthotopic 4T1 breast cancer model.

(A) Illustration of the experimental design. (B) Tumor growth curves and (C) ratio of tumor weight vs. body weight in different groups. Data are presented as mean ± SD (*P<0.05, **P<0.01). (D) 50 female BALB/c mice were randomly divided into 5 groups (n = 10). Tumor challenge and oral vaccination were performed as described. A Kaplan-meier survival curve is shown.