Table 1. Clinical, laboratory features and results of AAV patients without anti-GBM antibodies.
Parameters | Number (%) |
Number | 64 |
Male/female | 32/32 |
GPA/MPA | 21/43 |
Age (years) | 60.48±15.14 |
Scr (µmol/L) | |
Mean±SD | 339.11±237.71 |
Range | 70–1007 |
Renal insufficiency at diagnosis | 48 (75%) |
Urinary protein (g/24 hr) | |
Mean±SD | 2.09±1.83 |
Range | 0–7.25 |
ESR | 70.05±40.14 |
Constitutional symptoms | 49(76.6%) |
Skin rash | 7 (10.9%) |
Arthralgia | 15(23.4%) |
Muscle pain | 10 (15.6%) |
Hemoptysis | 10(15.6%) |
Lung involved | 43 (67.2%) |
ENT | 27(42.2%) |
Ophthalmic | 14(21.9%) |
Gastrointestinal | 11(17.2%) |
Nervous system | 10(15.6%) |
BVAS | 20.27±5.18 |
Glomeruli per biopsy | 24.55±11.69 |
Percentage of normal glomeruli (%) | 28.0±27.0 |
Glomerular lesions (%) | |
Total crescents | 60.58±27.19 |
Cellular crescents | 28.42±25.99 |
Number of patients’ sera with positive reactivity to recombined linear peptides (GPA/MPA) | |
P | 4/5 |
L | 3/8 |
H1 | 6/16 |
H2 | 6/11 |
H3 | 5/4 |
H4 | 5/8 |
[Abbreviations] GPA: granulomatosis with polyangiitis; MPA: microscopic polyangiitis; BVAS: Birmingham Vasculitis Activity Scores; ENT: ear, nose and throat; SD: standard deviation.