Table 2.
6 weeks | 12 weeks | |
---|---|---|
All IA patients (n = 88) | ||
All-cause mortality (95% CI)a | 0.51 (0.41, 0.62) | 0.60 (0.50, 0.70) |
Clinical failure in response to antifungal therapy (95% CI)a,b | 0.64 (0.54, 0.74)c | 0.62 (0.52, 0.72)d |
Patients with ≥2 BG values (n = 69) | ||
All-cause mortality (95% CI)a | 0.38 (0.27, 0.50) | 0.49 (0.38, 0.62) |
Clinical failure in response to antifungal therapy (95% CI)a,b | 0.54 (0.42, 0.66) | 0.51 (0.40, 0.63) |
95% CI: 95% confidence interval
As defined by 2008 EORTC/MSG consensus criteria for defining responses to antifungal therapy
At 6 weeks, 32 patients were considered clinical ‘successes’ (3 complete clinical responses, 29 partial responses) and 56 were considered clinical ‘failures’ (6 stable responses, 5 progressive disease, and 45 deaths).
At 12 weeks, 34 patients were considered clinical ‘successes’ (13 complete clinical responses, 21 partial responses) and 54 were considered clinical ‘failures’ (0 stable responses, 2 progressive disease, 52 deaths).