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ADHFE1 promoter methylation and mRNA expression with and without treatment with 5-aza-2-dC. (A) After treatment of 5-aza-2-dC, the relative methylation of ADHFE1 promoter was decreased in 9 of 12 CRC cell lines. (B) After treatment of 5-aza-2-dC, the expression of ADHFE1 mRNA was increased in 11 of 12 CRC cell lines.
