Table 5.
TGFβ pathway molecules grouped into genotypes with patterns
| TGFΒ3−/− | TGFΒ3+/− | WT | ||||
|---|---|---|---|---|---|---|
|
p1 |
p2 |
p1 |
p1 |
p2 |
p4 |
p8 |
| Acvr1 |
Tgfβ1 |
Acvr1 |
Bmp2 |
Acvr1 |
Inhba |
Bmp4 |
| Bmp2 |
|
Bmp2 |
Map2k2 |
Bmp7 |
Kras |
Crebbp |
| Bmp4 |
|
Bmp4 |
TGFβr1 |
Grb2 |
Map2k1 |
Smad3 |
| Bmp7 |
|
Bmp7 |
|
Inhbb |
Nkx2-5 |
Tgfβ2 |
| Crebbp |
|
Crebbp |
|
Runx2 |
|
|
| Grb2 |
|
Grb2 |
|
Tgfβ1 |
|
|
| Inhba |
|
Inhba |
|
Tgfβ3 |
|
|
| Inhbb |
|
Inhbb |
|
TGFβr2 |
|
|
| Kras |
|
Kras |
|
|
|
|
| Map2k1 |
|
Map2k1 |
|
|
|
|
| Map2k2 |
|
Map2k2 |
|
|
|
|
| Nkx2-5 |
|
Nkx2-5 |
|
|
|
|
| Runx2 |
|
Runx2 |
|
|
|
|
| Smad3 |
|
Smad3 |
|
|
|
|
| Tgfβ2 |
|
Tgfβ1 |
|
|
|
|
| Tgfβ3 |
|
Tgfβ2 |
|
|
|
|
| TGFβr1 |
|
Tgfβ3 |
|
|
|
|
| TGFβr2 |
|
TGFβr1 |
|
|
|
|
| TGFβr2 | ||||||