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. 2013 Apr 5;8(4):e60414. doi: 10.1371/journal.pone.0060414

Figure 5. A: PDGFR-α and α-SMA mRNA expression with PDGFR-α siRNA.

Figure 5

RGS for PDGFR-α mRNA and α-SMA mRNA expression by cultured fibroblasts from SSc skin lesions left untreated fibroblasts (NC), fibroblasts treated with PDGF-AA+siRNA negative control (P-siNC), fibroblasts stimulated with PDGF-AA (P), and fibroblasts treated with PDGF-AA+PDGFR-α siRNA (P-si). PDGFR-α mRNA and α-SMA mRNA expression was determined by RT-PCR. β-actin mRNA served to normalize expression of mRNA. B: Quantification of the data. PDGFR-α siRNA reduces PDGFR-α mRNA and α-SMA mRNA expression in SSc fibroblasts.