Skip to main content
. 2013 Apr 5;8(4):e59554. doi: 10.1371/journal.pone.0059554

Figure 2. PrPC inversely correlates with BACE1 activity, Aβ load, soluble and insoluble Aβ and Braak stage.

Figure 2

Relative PrPC protein levels were plotted against BACE1 activity (A), Aβ load (B), soluble Aβ (C), insoluble Aβ (D) and Braak stage (E) for each subject in the cohort (n = 48. Control, filled circles; AD, empty circles). PrPC significantly inversely correlates with BACE1 activity, Aβ load, soluble Aβ, insoluble Aβ and Braak stage as determined by Spearman's rank correlation coefficient (rs).