Table 1. Summary data of the sporadic AD and age-matched control samples.

Characteristic	Control (n = 24*)	AD (n = 24)	p value
Age (y)	76.46±2.72	82.50±1.44	0.204
PM delay (h)	38.50±6.27	51.08±4.11	0.100
APOE ε4 allele (%)	13%	75%	<0.001
NSE (pg/ml)	0.51±0.05	0.51±0.05	0.992
PrPC protein (arbitrary units)	1.00±0.19	0.51±0.11	0.014
CNTN5 protein (arbitrary units)	1.00±0.17	2.78±0.96	0.167
BACE1 activity (relative fluorescence units)	2314.79±133.28	2720.45±169.71	0.066
Soluble Aβ (nM)	1.62±0.36	2.54±0.71	0.391
Insoluble Aβ (nM)	20.44±6.56	138.92±16.41	<0.001
Aβ load (%)	0.04±0.04	2.42±0.59	<0.001
Braak stage	1.33±0.23	5.08±0.16	<0.001

All data are mean ± SEM unless stated. *n = 20 for control Aβ load analysis.