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. 2013 Apr 5;8(4):e61025. doi: 10.1371/journal.pone.0061025

Figure 1. Correlates of PiB-binding in CBS patients. A.

Figure 1

– Impaired sentence repetition was detected in 75% of PiB-positive patients (defined as an SUVR ratio of >1.5) compared to only 22.2% of PiB-negative patients (P = 0.07). B – There was a trend (P = 1.06) for a correlation between increased PiB-binding (reflected in increased SUVR ratio) and functional impairment (reflected by an increased CBI total). C – Increased PiB-binding (reflected by an increased SUVR) was strongly and highly significantly (P<0.001) correlated with visuospatial dysfunction. Note – PiB = Pittsburgh Compound B, SUVR = standardized uptake value ratio, CBI = Cambridge Behavioural Inventory, VOSP = Visual Object and Space Perception Battery. In Figure 1B and 1C the line of best fit is shown, with 95% confidence bands.