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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: J Cardiovasc Electrophysiol. 2012 Dec 21;24(4):457–463. doi: 10.1111/jce.12060

Figure 2. Cellular substrates that affect abnormal impulse induction.

Figure 2

A: Low concentration of the LTCC blocker nifedipine eliminated abnormal impulses in KO myocytes. B: SR Ca2+ leak was reduced in KO myocytes at all tested frequencies, compared to that recorded from WT myocytes. C: Mean values of normalized SR Ca2+ leak measured in WT (n=10) and KO (n=15) myocytes. D: There is no difference in diastolic Ca2+ between WT (n=18) and KO myocytes (n=24). Error bars denote S.E.M.; NT: normal Tyrode’s solution.