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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: J Cardiovasc Electrophysiol. 2012 Dec 21;24(4):457–463. doi: 10.1111/jce.12060

Figure 3. APD prolongation and abnormal impulse induction.

Figure 3

A: Application of the K+ channel blocker 4-AP significantly prolonged APD but failed to promote abnormal impulses in WT ventricular myocyte. B: In the presence of the LTCC opener S(−)Bay K8644, automaticity was induced in WT ventricular myocytes at a lowered Gsac level. C: SAC-induced automaticity in the presence of AIP and ISO. D: APD prolongation by 4-AP and ISO, respectively.