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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Cancer Res. 2013 Jan 30;73(7):2127–2138. doi: 10.1158/0008-5472.CAN-12-4184

Table 1.

CD20loCD19+ B cells from B-CLL patients suppress T cells

Patients Compared to ND Rituximab
CD20 decrease * Suppression 4-1BBL
1 + +++ Low +
Low
2 ND
ND
3 + +++ Low +
4 + ++ Low
5 + ++ Low
6 + ++ Equal +
7 + + ND +
8 + + High
9 Equal
10 High
11 Equal
12 + Low +
13 + ++ low +

CD19+ B cells from B-CLL patients were phenotyped for CD20 and 4-1BBL expression and tested for T cell suppression

*

+ corresponds to > 40% decrease compared to ND