Table 3. Broad-spectrum compounds active against two or more bacteria.
| Bacillus anthracis | Fransciella tularensis | Coxiella burnetii | |||||
| Compound | Conc. (µM) | Approved indication | ICR (% protection)a | Broth (% protection) | ICR (% protection) | Broth (% protection) | ICR (% protection) |
| Clindamycin | 50 | antibacterial | 92 | + | 83 | + | 0 |
| Dirithromycin | 50 | antibacterial | 92 | + | 88 | + | 0 |
| Erythromycin | 50 | antibacterial | 96 | + | 104 | + | 100 |
| Gemifloxacin | 50 | antibacterial | 97 | − | 91 | − | 0 |
| Lomefloxacin | 50 | antibacterial | 95 | + | 98 | + | 100 |
| Minocycline | 50 | antibacterial | 95 | − | 92 | − | 0 |
| Norfloxacin | 50 | antibacterial | 105 | + | 83 | + | 0 |
| Netilmicin | 50 | antibacterial | 98 | + | −2 | + | 100 |
| Oxytetracycline | 50 | antibacterial | 94 | + | 92 | + | 0 |
| Tetracycline | 50 | antibacterial | 105 | + | 103 | + | 0 |
a
+: growth inhibition; −: no growth inhibition; ICR: intracellular replication.