Table 4.
Comparison of detection of class mutations by standard genotypic sequencing and ultra-deep sequencing; N=13
| Subject | Standard sequencing | Ultra-deep sequencing |
|---|---|---|
| 1 | WT | PI, NRTI, NNRTI |
| 2 | PI, NRTI, NNRTI | PI, NRTI* |
| 3 | NRTI | NRTI,NNRTI |
| 4 | WT | WT |
| 5 | NRTI | WT* |
| 6 | NNRTI | PI, NRTI, NNRTI |
| 7 | WT | WT |
| 8 | WT | WT |
| 9 | WT | NNRTI |
| 10 | NNRTI | NRTI, NNRTI |
| 11 | PI, NRTI, NNRTI | PI, NRTI, NNRTI |
| 12 | PI, NRTI, NNRTI | PI, NRTI, NNRTI |
| 13 | WT | WT |
Abbreviations used in table: WT=wildtype, PI=protease inhibitor mutation, NRTI=nucleoside reverse transcriptase inhibitor mutation, NNRTI=non-nucleoside reverse transcriptase inhibitor mutation.
*
Ultra-deep sequencing detected fewer mutations than standard sequencing in two samples.