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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Pharm Res. 2013 Jan 30;30(5):1435–1446. doi: 10.1007/s11095-013-0984-9

Fig. 1. Isobolograms (A) and (B) Combination Index (CI) values of the interaction between Cxb with Doc against human lung Cancer cells.

Fig. 1

Different concentrations of Cxb were employed to study the effect on IC50 of Doc. Variable ratios of drug concentrations and mutually non-exclusive equations were used to determine the CI. The CI values represent mean of four experiments. CI >1.3: antagonism; CI 1.1–1.3: moderate antagonism; CI 0.9–1.1: additive effect; CI 0.8–0.9: slight synergism; CI 0.6–0.8: moderate synergism; CI 0.4–0.6: synergism; CI 0.2–0.4: strong synergism.