Skip to main content
. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Pharm Res. 2013 Jan 30;30(5):1435–1446. doi: 10.1007/s11095-013-0984-9

Fig. 2. Effects of Cxb-NLC and Doc on metastatic A549 lung tumor weight (A); metastatic A549 lung tumor volume (B); mice body weight (C).

Fig. 2

A549 cells (2 × 106) were injected into the nude mice by tail vein. Tumors were established for 7 days before therapy. Tumors from animals treated with Cxb-NLC aerosol (3 times a week), 10 mg/kg Doc (days 14, 18, 22), or combination were harvested after 28 days. Lung weights and tumor volumes were determined for measurement of therapeutic activity of the treatments. One-way ANOVA followed by post Tukey test was used for statistical analysis. P < 0.05 (*, significantly different from untreated controls; **, significantly different from single treatments). Data presented are means ± SD (n =8).