Figure 1. Study design and experiment schemes.
The study design (top) and experiment scheme (bottom) of Experiment 1, which tested the effects of nicotine on promoting lung tumor and emphysema development (A), and Experiment 2, which tested the effect of BCX supplementation on the promotion of lung tumor and emphysema development (B) are shown. Abbreviations: BCX (10): β-cryptoxanthin at 10 mg/kg diet; BCX (20): β-cryptoxanthin at 20 mg/kg diet; C: control; i.p.: intraperitoneal; Nic: nicotine; NNK: 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; wk: week(s).