Scheme 1. Asymmetric Synthesis of Compound 7a.
aReagents and conditions: (a) (Boc)2O, DMAP, DIEA, DCM, reflux; (b) (S)-2-methyl-CBS-oxazoborolidine, BH3·Me2S, THF; (c) phthalimide, DIAD, PPh3, THF; (d) N2H4·H2O, EtOH.
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