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. 2012 Jun 26;72(5):728–735. doi: 10.1136/annrheumdis-2012-201381

Figure 1.

Figure 1

(A) Gene expression of 11 interferon (IFN) type I inducible genes in patients with primary Sjögren's syndrome (pSS) (n=69) and healthy controls (HC) (n=44). To compare means the Mann–Whitney U test was applied. (B) Heat map showing gene expression of five interferon (IFN) type I inducible genes in monocytes of patients with pSS (n=69) and HC (n=44). On the left the patients with pSS are depicted and subdivided into IFN type I signature-positive patients and IFN type I signature-negative patients. On the right the HC are depicted. Red colour indicates high gene expression. (C) Distribution of IFN scores in IFN type I signature-positive and -negative patients and HC. IFN type I-positive cases are depicted in red. Blue lines depict medians. (D) Heat map showing gene expression of IFN type I inducible genes in monocytes of patients with pSS (n=24) at two different time points (average period between two measurements 3.6±2.5 years). (E) No significant differences detected between two time points using the dependent t test.