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. Author manuscript; available in PMC: 2013 Apr 6.
Published in final edited form as: Clin Cancer Res. 2011 Aug 1;17(18):5867–5877. doi: 10.1158/1078-0432.CCR-11-0737

Figure 2. Significantly-enriched canonical pathways identified by Ingenuity Pathway Analysis of the genes differentially regulated in pre- vs. post-surgery PBMC samples of lung cancer patients.

Figure 2

A. Significant pathways. Numbers in shaded bars indicate genes in the pathway expressed at significantly higher (black) or lower (grey) levels pre-surgery. Numbers in white bars indicate unchanged genes. All are signaling pathways, except for the aminophosphonate metabolic pathway. P-values were corrected for multiple comparisons using the Benjamini-Hochberg correction. B. Venn diagram shows the gene overlap between the 3 most-significant pathways (listed in Supplementary Table 4). Five genes (AKT3, KRAS, PIK3R1, PRKCZ, and RAF1) are shared by the three pathways.