. Author manuscript; available in PMC: 2013 Apr 7.

Published in final edited form as: Genesis. 2010 Aug;48(8):492–504. doi: 10.1002/dvg.20650

Table 2.

Treatment With SU5402 Causes Defects in Cardiac Looping Morphology

Phenotypic analysis after treatment with SU5402
Treatment (No. of Embryos)	Untreated (n = 22)	DMSO (n = 34)	SU5402 (n = 35)
Anterior defect	0 (0%)	1 (3%)	1 (3%)
Middle–ventral region edema	0 (0%)	0 (0%)	4 (11%)
Pericardial edema	0 (0%)	0 (0%)	12 (34%)
Unlooped heart	0 (0%)	0 (0%)	33 (94%)

Embryos were scored for gross morphology in three separate experiments. As shown, SU5402 induced edema and cardiac looping defects. Several embryos exhibited both edema and an unlooped heart, therefore the totals do not add up to 100%.