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. Author manuscript; available in PMC: 2013 Apr 7.
Published in final edited form as: Gastroenterology. 2011 Dec 16;142(4):918–927.e6. doi: 10.1053/j.gastro.2011.12.017

Figure 1. VEGF is required to maintain LSEC phenotype both in vitro and in vivo.

Figure 1

(A) Representative SEM of LSEC cultured with (left panel) and without (right panel) VEGF for 2 days show loss of fenestrae in sieve plates in vitro in the absence of VEGF. Scale bar, 5μm. (B) Hepatic expression of VEGF on immunoblot with densitometry and (C) representative SEM of hepatic sinusoids from rats treated with VEGF ASO or control oligonucleotides. * p<0.05. Scale bar, 2μm. All figures represent n ≥ 3.