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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2013 Mar 1;62(3):e82–e86. doi: 10.1097/QAI.0b013e318278e976

Table 2.

Frequency, prevalence, sensitivity, specificity, PPV and NPV for predicting doctor behavior by individual and combined criteria for non-stable patients

Gold Standard Predictor Predictor Statistics
Frequency Prevalence, % (95% CI) Sensitivity, % (95% CI) Specificity, % (95% CI) PPV, % (95% CI) NPV, % (95% CI)
Individual Criterion of Non-Stable Visits

ARV Change Detectable Viral Load 37,380 26.8 (26.5 – 27.0) 31.1 (30.0 – 32.1) 73.5 (73.2 – 73.7) 6 (5.8 – 6.3) 95.1 (95 – 95.3)
ARV Change Weight change > 5% from previous visit 25,914 18.6 (18.3 – 18.8) 22.8 (21.8 – 23.8) 81.7 (81.5 – 81.9) 6.4 (6.1 – 6.7) 95.1 (95 – 95.2)
ARV Change Declining CD4+ count or low CD4+ count combined with undetectable viral load 18,061 12.9 (12.8 – 13.1) 13.3 (12.5 – 14.1) 87.1 (86.9 – 87.3) 5.3 (5 – 5.6) 94.8 (94.7 – 95)
ARV Change Comorbid Condition 15,831 11.3 (11.2 – 11.5) 73.9 (72.9 – 74.9) 92.1 (91.9 – 92.2) 33.7 (33 – 34.5) 98.5 (98.4 – 98.5)
ARV Change Recent Regimen Change (< 3 months) 12,939 9.3 (9.1 – 9.4) 4.4 (3.9 – 4.9) 90.5 (90.3 – 90.6) 2.4 (2.2 – 2.7) 94.5 (94.4 – 94.7)
ARV Change Currently Pregnant 3,003 2.1 (2.1 – 2.2) 4.0 (3.6 – 4.5) 98.0(97.9 – 98.0) 9.7 (8.7 – 10.8) 94.9 (94.8 – 95)
ARV Change ART Problem 167 0.1 (0.1 - 0.1) 0.7 (0.5 – 0.9) 99.9 (99.9 - 99.9) 29.9 (23.1 – 37.5) 94.9 (94.7 – 95)

Combined Criteria of Non-Stable Visits

ARV Change Patient Not Stable 79,540 56.9 (56.7 – 57.2) 88.9 (88.2 – 89.7) 44.8 (44.5 – 45.1) 8.1 (7.9 – 8.3) 98.7 (98.6 – 98.8)
Visit Less than 28 days Patient Not Stable 71,104 56.6 (56.3 – 56.9) 72.6 (71.8 – 73.4) 45.1 (44.8 – 45.4) 12.1 (11.9 – 12.3) 94.0 (93.8 – 94.2)
Visit Less than 14 days Patient Not Stable 71,104 56.6 (56.3 – 56.9) 75.6 (74.0– 77.1) 43.9 (43.6– 44.2) 3.3 (3.2 – 3.4) 98.6 (98.5 – 98.7)
ARV Change or Visit Less than 28 days Patient Not Stable 79,540 56.9 (56.7 – 57.2) 77.6 (77 – 78.2) 46.1 (45.8 – 46.4) 17.4 (17.1 – 17.6) 93.4 (93.2 – 93.6)
ARV Change or Visit Less than 14 days Patient Not Stable 79,540 56.9 (56.7 – 57.2) 84.6 (83.9 – 85.3) 45.2 (44.9 – 45.5) 10.7 (10.5 – 10.9) 97.4 (97.3 – 97.6)