Table 1. Body weight, heart weight and the ratio of heart weight to body weight.
SHR-SP | |||||
---|---|---|---|---|---|
Parameters |
WKY rats |
Placebo (n=6) |
Valsartan (n=6) |
Valsartan+amlodipine (n=6) |
Valsartan+cilinidipine (n=6) |
Body weight (g) | 272±3.0** | 206±3.3 | 204 ±4.8 | 206±4.2 | 205±3.5 |
Heart weight (mg) | 768±18 | 820±30 | 698±9* | 707±16* | 705±16* |
Heart weight/body weight (mg/g) | 2.82±0.07** | 3.98±0.10 | 3.43±0.06** | 3.43±0.06** | 3.44±0.05** |
Values are mean±s.e.m. *P<0.05 and **P<0.01 vs. placebo.