Table 2. The association between HAART use and incidence of Kaposi's sarcoma of the MACS HIV-infected men in current study, stratified by current smoking status and HAART use.
|
KS incidence cases |
Follow-up (person-years)b |
Unadjusted model |
Adjusted modela |
||||
---|---|---|---|---|---|---|---|---|
HR | 95% CI | P-value | HR | 95% CI | P-value | |||
Current Smoking: no |
336 |
15 609 |
|
|
|
|
|
|
HAART ever use | ||||||||
No | Ref. | Ref. | ||||||
Yes |
|
|
0.08 |
0.06–0.12 |
<0.0001* |
0.28 |
0.16–0.49 |
<0.0001* |
Current Smoking: yes |
192 |
10 949 |
|
|
|
|
|
|
HAART ever use | ||||||||
No | Ref. | |||||||
Yes |
|
|
0.13 |
0.08–0.20 |
<0.0001* |
0.60 |
0.28–1.12 |
0.10 |
HAART use: no |
55 |
13 094 |
|
|
|
|
|
|
Current smoking | ||||||||
No | Ref. | Ref. | ||||||
Yes |
|
|
0.78 |
0.64–0.94 |
0.01* |
0.57 |
0.35–0.92 |
0.02* |
HAART use: yes |
473 |
13 164 |
|
|
|
|
|
|
Current smoking | ||||||||
No | Ref. | Ref. | ||||||
Yes | 1.20 | 0.71–2.05 | 0.50 | 1.09 | 0.52–2.92 | 0.82 |
Abbreviations: CI: confidence interval; HR=hazard ratio; Ref.=Reference category.
The model was adjusted for age, race/ethnicity, employment status, education, individual gross income, enrolment, and CD4 cell count.
The follow-up time was for both KS and non-KS incidence cases.
*: P-value<0.05.