Table 2b.
Univariable | Multivariable | |||
---|---|---|---|---|
HR (95% CI) | p-value | HR (95% CI) | p-value | |
Age (y) | 0.0009 | 0.0004 | ||
Group A <55 | 1.49 (0.90-2.46) | 0.13 | 1.32 (0.77-2.27) | 0.32 |
Group B 55 - 64 | 1.05 (0.73-1.50) | 0.81 | 0.98 (0.68-1.42) | 0.91 |
Group C 65 - 74 | Reference | Reference | ||
Group D ≥75 | 2.58 (1.58-4.21) | 0.0002 | 2.84 (1.70-4.74) | <.0001 |
Stage at Dx | <.0001 | <.0001 | ||
1-2 | Reference | Reference | ||
3 | 0.94 (0.61 - 1.46) | 0.79 | 0.92 (0.58 -1.47) | 0.72 |
4 | 3.04 (2.03 - 4.55) | <.0001 | 2.83 (1.70 -4.72) | <.0001 |
Gleason Score | 0.0007 | 0.0008 | ||
<=6 | Reference | Reference | ||
7 | 1.31 (0.65 - 2.61) | 0.45 | 1.41 (0.68 -2.93) | 0.36 |
8-10 | 2.34 (1.22 - 4.50) | 0.01 | 2.57 (1.28 -5.17) | 0.008 |
CCI at Dx | 0.71 | 0.52 | ||
0 | Reference | Reference | ||
1-2 | 0.95 (0.68 - 1.32) | 0.75 | 0.91 (0.64 -1.31) | 0.62 |
3+ | 1.17 (0.72 - 1.91) | 0.53 | 1.23 (0.72 -2.08) | 0.45 |
RT at Dx | 0.001 | 0.32 | ||
No | Reference | Reference | ||
Yes | 0.58 (0.42 - 0.80) | 0.82 (0.56 -1.21) | ||
PSA at Diagnosis | 0.003 | 0.34 | ||
0 - <10 | Reference | Reference | ||
10 - <20 | 0.87 (0.55 - 1.37) | 0.55 | 0.95 (0.58 -1.54) | 0.82 |
20 - <100 | 0.83 (0.56 - 1.24) | 0.37 | 0.71 (0.46 -1.08) | 0.10 |
≥100 | 1.84 (1.17 - 2.89) | 0.008 | 0.75 (0.45 -1.26) | 0.28 |
Prostatectomy at Dx | 0.08 | 0.06 | ||
No | Reference | Reference | ||
Yes | 0.69 (0.46 - 1.05) | 0.65 (0.41 -1.02) |