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. 2013 Mar 21;4(4):304–314. doi: 10.7150/jca.4192

Table 2b.

Univariable and Multivariable Cox-PH Regression Analysis of Overall Survival.

Univariable Multivariable
HR (95% CI) p-value HR (95% CI) p-value
Age (y) 0.0009 0.0004
Group A <55 1.49 (0.90-2.46) 0.13 1.32 (0.77-2.27) 0.32
Group B 55 - 64 1.05 (0.73-1.50) 0.81 0.98 (0.68-1.42) 0.91
Group C 65 - 74 Reference Reference
Group D ≥75 2.58 (1.58-4.21) 0.0002 2.84 (1.70-4.74) <.0001
Stage at Dx <.0001 <.0001
1-2 Reference Reference
3 0.94 (0.61 - 1.46) 0.79 0.92 (0.58 -1.47) 0.72
4 3.04 (2.03 - 4.55) <.0001 2.83 (1.70 -4.72) <.0001
Gleason Score 0.0007 0.0008
<=6 Reference Reference
7 1.31 (0.65 - 2.61) 0.45 1.41 (0.68 -2.93) 0.36
8-10 2.34 (1.22 - 4.50) 0.01 2.57 (1.28 -5.17) 0.008
CCI at Dx 0.71 0.52
0 Reference Reference
1-2 0.95 (0.68 - 1.32) 0.75 0.91 (0.64 -1.31) 0.62
3+ 1.17 (0.72 - 1.91) 0.53 1.23 (0.72 -2.08) 0.45
RT at Dx 0.001 0.32
No Reference Reference
Yes 0.58 (0.42 - 0.80) 0.82 (0.56 -1.21)
PSA at Diagnosis 0.003 0.34
0 - <10 Reference Reference
10 - <20 0.87 (0.55 - 1.37) 0.55 0.95 (0.58 -1.54) 0.82
20 - <100 0.83 (0.56 - 1.24) 0.37 0.71 (0.46 -1.08) 0.10
≥100 1.84 (1.17 - 2.89) 0.008 0.75 (0.45 -1.26) 0.28
Prostatectomy at Dx 0.08 0.06
No Reference Reference
Yes 0.69 (0.46 - 1.05) 0.65 (0.41 -1.02)