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. 2013 May 10;18(14):1777–1788. doi: 10.1089/ars.2012.4836

FIG. 9.

FIG. 9.

Depolarization mediates EGFR-dependent Rac1 activation in arteries from CH but not control rats. Representative Western blots and mean densitometric data for GTP bound (active) Rac1 normalized to total Rac1 in homogenates from control and CH intrapulmonary arteries. Active Rac1 was measured under baseline conditions and following 10 min stimulation with KCl (60 mM) or KCl plus the EGFR inhibitor, AG1478 (1 μM). Values are means±SE of n=4 rats/group; *p<0.05 vs. control KCl; #p<0.05 vs.CH vehicle; τp<0.05 vs. CH KCl.