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Protection of siRNA degradation by cSCK-pa100. siRNA481 (0.77 μM final concentration) alone or complexed with PAEA128-b-PS40 cSCK-pa100 (50 μg/mL, N/P=10:1) or Lipofectamine 2000 (13 and 200 μg/mL) was incubated in 50% human serum (Sigma) at 37°C, under 5% CO2 for the times shown, electrophoresed on a 2% agarose gel, and visualized by staining with ethidium bromide.
