Fig. 3.

dCK immunolabeling patterns in an untreated primary infiltrating pancreatic cancer (A) and a matched lung metastasis that developed two years later following gemcitabine therapy (B). Strong positive (3+) immunolabeling of the nucleus and cytoplasm is seen within the neoplastic cells of the untreated primary tumor. In contrast, a significant reduction in dCK immunolabeling (1+) was found in the metastatic disease from this patient (original magnification, ×200).