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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 May 10;32(7):1624–1631. doi: 10.1161/ATVBAHA.112.246066

Table 3.

Biliary lipid secretion

Flow rate Cholesterol Phospholipids Bile acid
Control-V 42.4±4.3a 24.2±2.9a 246.9±23.4a 1455.3±362.6a
Control-T 86.8±16.0b 74.4±17.9b 251.2±31.9a 2069.6±94.8a
MttpIKO-V 88.2±4.6b 104.6±17.3b 315.1±26.7a 2101.8±414.6a
MttpIKO-T 86.4±7.6b 92.98±6.1b 235.4±12.6a 2550.2±301.8a

Control and MttpIKO mice (n=7–17) were treated either vehicle (V) or T0901317 (T) for 7 days. Bile samples were collected for 1 hour. The flow rate was expressed as μl/min/kg body weight. Biliary cholesterol, phospholipids and bile acids were analyzed (Methods). Biliary lipid secretion was expressed as nmol/min/Kg body weight. The difference between values associated with different superscript letters for the parameters indicated in each vertical column is statistically significant (p<0.05).