Skip to main content
. 2013 Feb 8;20(5):698–708. doi: 10.1038/cdd.2012.165

Table 1. Reported reactivities of commercially available crossreactive anti-LPS mAbs used in these studies.

mAb LPS specificity Species Isotype
15306 Shigella sonnei Salmonella typhimurium Serratia marcescens Proteus mirabilis Proteus vulgaris Acinetobacter calcoaceticus Mouse IgG2a
15308 Enterobacter aerogenes Serratia marcescens Proteus mirabilis Acinetobacter calcoaceticus Pseudomonas aeruginosa Mouse IgG3
15174 Chlamydia trachomatis Mouse IgG2a

Antibodies were assessed by ELISA for binding to purified LPS. LPS of Chlamydia trachomatis lacks the O-polysaccharide region most distal to lipid A. Thus, although being marketed as anti-Chlamydia antibody, mAb 15174 was chosen for its potential reactivity towards conserved core regions of LPS.