Table 3.

Lung publication characteristics, estimated costs, and effectiveness.

Reference	Country	Type of study	Procedures compared	Perspective	Cost types	Local currency	Procedures cost per patient	Effectiveness	ICER/ICUR/Cost analysis results
Lanni et al. (2011)	USA	Cost-effectiveness	SBRT 3DCRT IMRT	Service provider	Direct	USD	SBRT: $52,471 3DCRT: $55,705 IMRT: $136,570	SBRT 36-month overall survival: 71% 3DCRT 36-month overall survival: 42% IMRT 36-month overall survival: n.a.	SBRT dominates
Sher et al. (2011)	USA	Cost-utility	SBRT 3DCRT RFA	Service provider	Direct	USD	SBRT: $51,133 3DCRT: $48,842 RFA: $44,648	SBRT: 1.91 QALY 3DCRT: 1.53 QALY RFA: 1.45 QALY	SBRT vs. 3DCRT: $6,000/QALY SBRT vs. RFA: $14,100/QALY
Puri et al. (2012)	USA	Cost-effectiveness	SBRT Surgery	Healthcare payer	Direct	USD	SBRT: $14,153 Surgery: $17,629	SBRT overall survival: 2.94 years Surgery overall survival: 3.39 years	Surgery vs. SBRT: $7,753/LYS

SBRT, stereotactic body radiation therapy; EBRT, external beam radiation therapy; 3DCRT, 3-dimensional conventional radiation therapy; IMRT, intensity modulated radiation therapy; RFA, radiofrequency ablation; USD, United States dollar; LY/LYS, life years/life year saved; QALY, quality adjusted life years; ICER, incremental cost-effectiveness ratio; ICUR, incremental cost-utility ratio.