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. 2013 Feb 19;108(6):1324–1331. doi: 10.1038/bjc.2013.65

Table 2. Multivariate analysis using the stepwise Cox regression procedures.

 
Univariatea
Multivariateb
Variables P-value HR 95% CI P-value
Sex
Male vs female
0.8064
2.673
1.098–6.504
0.0302
Age
⩾60 vs <60
0.0243
2.841
1.121–7.194
0.0277
Location
U vs ML
0.0370
 

 
Histological type
Undifferentiated vs differentiated
0.9078
 

 
Tumour size (mm)
⩾35 vs <35
<0.0001
 

 
Venous invasion
Positive vs negative
<0.0001
2.865
1.183–6.944
0.0195
Lymphatic invasion
Positive vs negative
<0.0001
 

 
pT-stage
T3–4 vs T1–2
<0.0001
20.833
2.577–166.667
0.0044
pN-stage
N2-3 vs N0-1
<0.0001
7.692
2.770–21.28
<0.0001
YWHAZ expression
High vs low 0.0190 2.307 1.003–5.304 0.0491

Abbreviations: CI=confidence interval; HR=hazard ratio.

Note: significant values are in boldface type.

a

The Kaplan–Meier method, and significance was determined by log-rank test.

b

Multivariate survival analysis was performed using Cox proportional hazard model.