Table 2. Multivariate analysis using the stepwise Cox regression procedures.
|
Univariatea |
Multivariateb |
||
---|---|---|---|---|
Variables | P-value | HR | 95% CI | P-value |
Sex | ||||
Male vs female |
0.8064 |
2.673 |
1.098–6.504 |
0.0302 |
Age | ||||
⩾60 vs <60 |
0.0243 |
2.841 |
1.121–7.194 |
0.0277 |
Location | ||||
U vs ML |
0.0370 |
|
— |
|
Histological type | ||||
Undifferentiated vs differentiated |
0.9078 |
|
— |
|
Tumour size (mm) | ||||
⩾35 vs <35 |
<0.0001 |
|
— |
|
Venous invasion | ||||
Positive vs negative |
<0.0001 |
2.865 |
1.183–6.944 |
0.0195 |
Lymphatic invasion | ||||
Positive vs negative |
<0.0001 |
|
— |
|
pT-stage | ||||
T3–4 vs T1–2 |
<0.0001 |
20.833 |
2.577–166.667 |
0.0044 |
pN-stage | ||||
N2-3 vs N0-1 |
<0.0001 |
7.692 |
2.770–21.28 |
<0.0001 |
YWHAZ expression | ||||
High vs low | 0.0190 | 2.307 | 1.003–5.304 | 0.0491 |
Abbreviations: CI=confidence interval; HR=hazard ratio.
Note: significant values are in boldface type.
The Kaplan–Meier method, and significance was determined by log-rank test.
Multivariate survival analysis was performed using Cox proportional hazard model.