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Cdc42, a Member of the Rho Family of GTPases as an Example of a Node
Cdc42 may be stimulated both by receptor-tyrosine kinases (RTK) as well as G protein–coupled receptors (GPCR), and in turn regulate different cellular functions by regulating the distinct downstream kinases Pak, S6K (S6-kinase), or the serum response factor (SRF).
