Table 3a. Univariate Cox proportional-hazards modeling for prediction of OS.
| Variable | Hazard ratio | Lower 95% CI for HR | Upper 95% CI for HR | Log-rank P-value | |
|---|---|---|---|---|---|
| Pre-PET | 2.57 | 1.08 | 6.12 | 0.034 | Neg vs Pos |
| Post-PET | 2.01 | 0.90 | 4.49 | 0.087 | Neg vs Pos |
| Any PET | 2.62 | 1.30 | 5.28 | 0.007 | Neg vs Any Pos |
| Stage diagnosis | 1.03 | 0.52 | 2.05 | 0.933 | Stage I–III vs IV |
| Stage relapse | 1.29 | 0.65 | 2.58 | 0.468 | Stage I–III vs IV |
| B symptoms | 2.17 | 1.06 | 4.44 | 0.034 | No vs yes |
| Age | 1.00 | 0.98 | 1.03 | 0.787 | 1 year increase |
| Extra nodal disease | 1.28 | 0.62 | 2.64 | 0.512 | no vs yes |
| Hodgkin's disease | 0.81 | 0.36 | 1.82 | 0.613 | Hodgkin's vs NHL |
| LDH | 1.61 | 0.64 | 4.05 | 0.316 | normal vs above normal |
| CR | 0.51 | 0.23 | 1.14 | 0.103 | CR vs other responses |
| Duration of CR | 0.43 | 0.18 | 1.00 | 0.050 | ≤1year vs > 1year |
| sAA-IPI | 1.31 | 0.75 | 2.29 | 0.350 | 1 unit increase |
| Hdrisk | 2.09 | 0.83 | 5.30 | 0.119 | 1 unit increase |
| Abbreviations: CI=confidence intervals; HR=hazard ratios; Neg=negative; PET= positron emission; Pos=positive; sAA-IPI=secondary age-adjusted International Prognostic Indicator. | |||||
| Significant P-values (P<0.05) are in italics. | |||||
| Table 3b: Univariate cox proportional-hazards modeling for prediction of progression-free Survival | |||||
|---|---|---|---|---|---|
|
| |||||
| Variable | Hazard ratio | Lower 95% CI for HR | Upper 95% CI for HR | Log-rank P-value | Comparison |
| Pre-PET | 2.23 | 1.01 | 4.92 | 0.047 | Neg vs Pos |
| Post-PET | 2.43 | 1.20 | 4.95 | 0.014 | Neg vs Pos |
| Any PET | 2.56 | 1.36 | 4.82 | 0.004 | Neg vs Any Pos |
| Stage diagnosis | 1.50 | 0.80 | 2.80 | 0.204 | Stage I–III vs IV |
| Stage relapse | 1.60 | 0.85 | 2.99 | 0.144 | Stage I–III vs IV |
| B symptoms | 2.22 | 1.16 | 4.26 | 0.017 | No vs yes |
| Age | 1.01 | 0.99 | 1.04 | 0.391 | 1 year increase |
| Extra nodal disease | 1.33 | 0.69 | 2.55 | 0.390 | No vs yes |
| LDH | 1.41 | 0.59 | 3.37 | 0.437 | Normal vs above normal |
| CR at time of transplant | 0.70 | 0.35 | 1.37 | 0.297 | CR vs other responses |
| Duration of first CR | 0.79 | 0.40 | 1.57 | 0.508 | ≤1year vs >1year |
| sAAIPI | 1.20 | 0.72 | 2.00 | 0.489 | 1 unit increase |
| Hdrisk | 2.18 | 0.99 | 4.78 | 0.052 | 1 unit increase |
Abbreviations: CI=confidence intervals; HR=hazard ratios; Neg=negative; PET=positron emission tomography; Pos=positive; sAA-IPI=secondary age-adjusted International Prognostic Indicator.
Significant P-values (P<0.05) are in italics.