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Change in parasympathetic nervous system activity shown by circadian index in each group after 14 days.
| Treatment group | Percent change from baseline to Day 14 |
|---|---|
| Placebo (S1T2) | −25.55 |
| Trazodone (S1T1) | −18.11 |
| Sentra PM (S2T1) | 33.30 |
| Sentra PM/trazodone (S2T2) | 52.65 |
Notes: The circadian index was computed at baseline and Day 14. The baseline and Day 14 circadian index was expressed as a percent change from baseline.
