Table 2.

Serum and urinary measurements (mean ± SD, or median values). Patient's characteristics by estrogen use and menstrual history.

Laboratory test	Normal range	N	All patients	Amenorrheic women1	Current estrogen use	Eugonadal women
			N = 66	N = 38	N = 17	N = 11
Serum corrected calcium	[2.25–2.60 mmol/L]	64	2.35 ± 0 .09	2.34 ± 0.1	2.35 ± 0.1	2.36 ± 0.1
Serum phosphate	[0.80–1.4 mmol/L]	63	1.3 (0.3)	1.3 (0.2)	1.3 (0.2)	1.5 (0.4)
Serum creatinine	[35–88 µmol/L]	65	71.85 ± 11.32	71.9 ± 12.9	74.1 ± 8.4	67.8 ± 8.6
Serum protein	[61–79 g/L]	45	66.0 ± 6.4	65.9 ± 6.6	65.8 ± 6.4	66.4 ± 6.8
Serum albumin	[35–48 g/L]	64	38.26 ± 4.51	40.5 ± 4.5°	37.3 ± 3.6	38.1 ± 4.7
Serum osteocalcin	[8.8–29.7 μg/L]	44	20.49 ± 11.30	19.2 ± 11.2	19.3 ± 9.0	28.4 ± 14.1
Serum total alkaline phosphatase	[30–125 IU/L]	61	46 (18)	48 (21)	41 (10)*	51 (14)
Serum IGF-I	[116–447 ng/mL]	66	118 (86)	103 (81)	129 (81)	144 (133)
Serum IGFBP-3	[3.3–6.7 µg/mL]	34	4.63 ± 1.21	4.4 ± 1.3	4.9 ± 1.0	4.9 ± 1.2
Serum parathyroid hormone	[1.1–6.8 pmol/L]	58	3.1 (1.5)	3.0 (1.4)	3.0 (1.8)	3.7 (1.3)
25-hydroxyvitamin D	[25–120 nmol/L]	57	74 (43)	69 (36)	76 (66)	73 (65)
Urinary calcium/creatinine	[0.10–0.50 mmol/mmol]	59	0.37 (0.44)	0.6 (0.6)°	0.3 (0.3)	0.2 (0.3)
Urinary D-pyr/cr2	[4.2–18.2 nmol/mmol]	52	17.7 (10.1)	18.1 (7.0)	13.4 (11.0)	16.0 (10.1)
TRCaI/GFR3	[2.4–2.9 mmol/L GFR]	55	2.59 ± 0 .21	2.54 ± 0.2	2.64 ± 0.2	2.67 ± 0.2
TmPi/GFR4	[0.8–1.4 mmol/L GFR]	55	1.4 (0.3)	1.4 (0.3)	1.3 (0.3)	1.5 (0.5)

Age-adjusted normal values were taken into account.

¹At the time of evaluation, and including 3 patients taking oral contraceptives, but continuing to be amenorrheic.

²Deoxypyridinoline/creatinine.

³Renal tubular reabsorption of calcium index.

⁴Renal tubular reabsorption of phosphate.

°P < 0.05 versus current estrogen use and eugonadal women.

*P < 0.05 current estrogen versus eugonadal women.