Table 1.
Characteristics of the included studies.
| Study | Number of authors | Trial date report | Sample size |
Followup (day) |
Baseline comparison | AE | Outcomes measure |
Treatment group dosage | Angina |
|---|---|---|---|---|---|---|---|---|---|
| Chen 2009 | 1 | 1 | 100 | 15 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Angina |
| Chen et al. 2011 | 3 | 1 | 100 | 10 | 0 | 0 | SYM | GXN 20 mL/d + CG | Angina |
| Chen 2006 | 1 | 1 | 62 | 14 | 1 | 1 | SYM, ECG | GXN 20 mL/d + CG | Angina |
| Cheng and Zang 2010 | 2 | 1 | 43 | 14 | 1 | 0 | SYM | GXN 30 mL/d + CG | Unstable |
| Cheng et al. 2011 | 3 | 1 | 76 | 14 | 1 | 1 | SYM, ECG | GXN 30 mL/d + CG | Angina |
| Dong XP 2009 | 1 | 0 | 100 | 1 | 0 | 0.5 | SYM | GXN 20 mL/d | Angina |
| Fu and Meng 2011 | 2 | 0 | 47 | 10 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Angina |
| Fu et al. 2010 | 4 | 1 | 56 | 14 | 1 | 0 | SYM, ECG | GXN 200 ml + CG + shenmaiyin 40 ml | Angina |
| Gao et al. 2005 | 3 | 1 | 60 | 14 | 1 | 1 | SYM, ECG | GXN 20 mL/d | Angina |
| Gong et al. 2009 | 3 | 1 | 85 | 14 | 1 | 1 | SYM, ECG | GXN 20 mL/d + xueshuantong 20 ml | Stable |
| He and Meng 2007 | 1 | 1 | 49 | 15 | 1 | 0 | SYM | GXN 20 mL/d + CG | Unstable |
| He 2009 | 1 | 1 | 120 | 28 | 1 | 1 | SYM, ECG | GXN 30 mL/d + atorvastatin 10 mg | Unstable |
| Hou and Gao 2009 | 2 | 1 | 128 | 14 | 1 | 1 | SYM, ECG | GXN 20 mL/d + CG | Stable |
| Huang et al. 2011 | 4 | 0 | 120 | 7 | 1 | 1 | SYM | GXN 20 mL/d + CG + xueshuantong 400 mg | Angina |
| Jiang et al. 2010 | 3 | 1 | 116 | 10 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Unstable |
| Jiang 2009 | 1 | 1 | 68 | 20 | 1 | 1 | SYM, ECG | GXN 20 mL/d | Angina |
| Jiang et al. 2010 | 5 | 0 | 56 | 7 | 0 | 1 | SYM | GXN 30 mL/d | Angina |
| Kong 2009 | 1 | 0 | 100 | 14 | 1 | 1 | SYM | GXN 30 mL/d + CG | Unstable |
| Lan et al. 2006 | 3 | 1 | 64 | 14 | 1 | 1 | SYM | GXN 20 mL/d | Angina |
| Li and Jia 2011 | 2 | 1 | 200 | 14 | 1 | 0 | SYM, ECG | GXN 30 mL/d + CG | Angina |
| Li and Lei 2005 | 2 | 1 | 156 | 14 | 0 | 1 | SYM, ECG | GXN 20 mL/d + CG | Angina |
| Li et al. 2009 | 5 | 1 | 168 | 14 | 1 | 0 | SYM | GXN 20 mL/d + CG | Angina |
| Li and Ran 2009 | 2 | 1 | 160 | 10 | 1 | 1 | SYM | GXN 20 mL/d + CG | Angina |
| Li 2004 | 1 | 0 | 83 | 7 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Unstable |
| Liang and Feng 2010 | 2 | 0 | 120 | 14 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Unstable |
| Liu 2004 | 1 | 1 | 104 | 10 | 1 | 1 | SYM | GXN 20 mL/d + CG | Unstable |
| Liu and Li 2007 | 2 | 1 | 88 | 12 | 0 | 1 | SYM | GXN 20 mL/d + CG | Unstable |
| Liu 2005 | 1 | 1 | 80 | 30 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Unstable |
| Liu 2011 | 1 | 1 | 152 | 28 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Angina |
| Lu et al. 2006 | 3 | 1 | 68 | 30 | 1 | 0 | SYM | GXN 30 mL/d + CG | Angina |
| Ma and Peng 2008 | 2 | 1 | 120 | 14 | 1 | 0 | SYM | GXN 30 mL/d + CG | Unstable |
| Nie and Chen 2007 | 2 | 1 | 60 | 14 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Angina |
| Qiao and Wu 2004 | 2 | 0 | 81 | 28 | 1 | 1 | SYM, ECG | GXN 20 mL/d + CG | Stable |
| Song 2010 | 1 | 1 | 82 | 7 | 0 | 0.5 | SYM | GXN 20 mL/d + CG + diltiazem 90 mg/d | Unstable |
| Su 2009 | 1 | 1 | 90 | 15 | 0 | 1 | SYM, ECG | GXN 6 mL/d + CG | Angina |
| Sun 2010 | 1 | 1 | 90 | 14 | 1 | 0 | SYM, ECG | GXN 30 mL/d + CG | Unstable |
| Sun et al. 2006 | 5 | 1 | 98 | 15 | 0 | 0 | SYM | GXN 20 mL/d + CG | Angina |
| Tian and Wu 2006 | 2 | 1 | 62 | 14 | 1 | 1 | SYM | GXN 30 mL/d + CG | Unstable |
| Wan and Xu 2009 | 2 | 0 | 120 | 14 | 1 | 1 | SYM, ECG | GXN 30 mL/d + CG | Unstable |
| Wang 2007 | 1 | 1 | 100 | 14 | 1 | 1 | SYM, ECG | GXN 30 mL/d + CG | Angina |
| Wang 2011 | 1 | 1 | 85 | 14 | 1 | 1 | SYM, ECG | GXN 20 mL/d + CG | Unstable |
| Wang 2011 | 2 | 1 | 112 | 14 | 1 | 1 | SYM, ECG | GXN 20 mL/d + CG | Unstable |
| Wang and Ji 2008 | 2 | 1 | 60 | 14 | 0 | 0 | SYM, ECG | GXN 20 mL/d + CG | Unstable |
| Wang and Sun 2007 | 2 | 1 | 92 | 10 | 0 | 0 | SYM | GXN 20 mL/d + CG | Unstable |
| Wang 2005 | 2 | 1 | 60 | 15 | 1 | 0 | SYM | GXN 20 mL/d + CG | Unstable |
| Wang 2010 | 1 | 0 | 80 | 14 | 1 | 1 | SYM, ECG | GXN 20 mL/d + CG | Stable |
| Wang 2005 | 1 | 0 | 76 | 15 | 0 | 0 | SYM | GXN 20 mL/d + CG + shenmai 30 mL/d + tongxinluo 9 pills/d | Unstable |
| Wang 2005 | 1 | 1 | 60 | 14 | 1 | 1 | SYM | GXN 20 mL/d + CG | Unstable |
| Wang et al. 2011 | 4 | 1 | 60 | 14 | 1 | 1 | SYM | GXN 20 mL/d + CG | Unstable |
| Wu et al. 2008 | 3 | 0 | 108 | 14 | 1 | 0 | SYM | GXN 20 mL/d + CG | Angina |
| Wu et al. 2011 | 4 | 1 | 144 | 7 | 1 | 0 | SYM | GXN 20 mL/d + CG + shenmai 50 mL/d | Unstable |
| Xia 2011 | 1 | 1 | 90 | 14 | 1 | 0 | SYM, ECG | GXN 30 mL/d + CG | Unstable |
| Yang and Ma 2008 | 2 | 1 | 90 | 14 | 1 | 0 | SYM, ECG | GXN 30 mL/d + CG | Unstable |
| Ye et al. 2008 | 3 | 0 | 76 | 15 | 0 | 1 | SYM | GXN 20 mL/d + CG | Unstable |
| Yu and Wang 2009 | 2 | 1 | 75 | 15 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Angina |
| Yuan 2005 | 1 | 0 | 104 | 14 | 1 | 0 | SYM, ECG | GXN 20 mL/d + CG | Angina |
| Zhang 2005 | 1 | 1 | 60 | 14 | 1 | 0 | SYM, ECG | GXN 10 mL/d | Angina |
| Zhang 2010 | 1 | 1 | 240 | 15 | 1 | 1 | SYM, ECG | GXN 20 mL/d + CG | Unstable |
| Zhang 2004 | 1 | 1 | 102 | 14 | 1 | 1 | SYM, ECG | GXN 10 mL/d + CG + ginkgo leaf injection 10 mL/d | Angina |
| Zhang 2004 | 1 | 1 | 42 | 7 | 0 | 1 | SYM | GXN 20 mL/d + CG | Angina |
| Zhao et al. 2010 | 6 | 1 | 100 | 14 | 1 | 1 | SYM, ECG | GXN 10 mL/d + CG + xueshuangtong 120 mg | Unstable |
| Zhao and An 2008 | 2 | 1 | 90 | 28 | 1 | 1 | SYM, ECG | GXN 20 mL/d + CG + simvastatin 10–20 mg/d | Unstable |
| Zhao 2010 | 1 | 1 | 86 | 14 | 1 | 0 | SYM, ECG | GXN 30 mL/d + CG | Angina |
| Zhong et al. 2007 | 8 | 1 | 60 | 10 | 0 | 0 | SYM | GXN 20 mL/d + CG | Angina |
| Zhu 2005 | 1 | 1 | 80 | 15 | 0 | 0.5 | SYM, ECG | GXN 20 mL/d + CG | Unstable |
GXN is Guanxinning injection; LMWH is low molecular weight heparin; and shenmai is Shenmai injection. CG is interventions of control group; SYM is SYMPTOMS; ECG is electrocardiogram; and AE is adverse event. The column of “Trial date report” shows that study did (1) or did not (0) report the trial date. The column of “Baseline comparison” shows that the study did (1) or did not (0) report the baseline comparison between the treatment and control groups.