Table 1.
Observed ulcer area, inhibition percentage pH and mucus content stomach.
| Animal group | Pre-treatment (5 mL/kg dose) | pH of gastric content | Mucus content | Ulcer index (mm)2
(Mean ± S.E.M) |
Inhibition (%) |
|---|---|---|---|---|---|
| 1 | Tween80 (normal control) | 3.06a ± 0.09 | 1.95a ± 0.06 | ||
| 2 | Ethanol 95% (ulcer control) | 1.67b ± 0.15 | 0.99b ± 0.04 | 482.4a ± 30.89 | |
| 3 | Omeprazole (20 mg/kg) | 3.7a ± 1.14 | 4.5c ± 0.07 | 108b ± 9.60 | 78.42 |
| 4 | α-mangostin (10 g/kg) | 4.64d ± 0.1 | 1.875d ± 0.04 | 169.92c ± 75.05 | 66.04 |
| 5 | α-mangostin (30 mg/kg) | 3.20e ± 0.05 | 3.1e ± 0.01 | 128.16d ± 84.75 | 74.39 |
All values are expressed as mean ± standard error of the mean. Means with different superscripts are significantly different. The mean difference is significant at the 0.05 level. Groups with different superscript alphabets are statistically significant.